Mosby’s Drug Guide for Nursing Students 11th Edition Skidmore-Roth eBook

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  • Download: Mosby’s Drug Guide for Nursing Students 11th Edition eBook
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  • Published: 2015
  • ISBN-10: 0323170218
  • ISBN-13: 978-0323170215

Description

Mosby’s Drug Guide for Nursing Students 11th Edition eBook

Alphabetical Drugs – A – Pages 1 – 5 (Small Sample)

abacavir (Rx) 

(a-ba-ka9veer)

Ziagen 

Func. class.:╇╉Antiretroviral

Chem. class.:╇╉Nucleoside reverse transcriptase inhibitor (NRTI)

Pregnancy category

Inhibitory action against HIV;

Therapeutic outcome: 

In combination with other antiretro

CONTRAINDICATIONS: 

BLACK BOX WARNING: Hypersensitivity, moderate to severe hepatic disease

Precautions: 

BLACK BOX WARNING: Lactic acidosis

DOSAGE AND ROUTES 

Adult/adolescent $16 hr:╇╉PO 300 mg bid or 600 mg daily with other antiretrovirals

Adolescent ,16 yr/child $3 mo:╇╉PO 8 mg/ kg bid, max 300 mg bid with other antiretrovirals

Hepatic dose 

Adult:╇╉(Child-Pugh 5-6) PO oral/sol 200 mg bid; severe hepatic disease, do not use

Available forms: 

Implementation 

PO route 

• May give without regard to food q12hr around the clock

• Give in combination with other antiretrovirals with or without food; do not use triple therapy as a beginning treatment, resistance may occur

• Store in cool environment; protect from light; do not freeze

ADVERSE EFFECTS 

CNS: 

GI: 

HEMA: 

INTEG: 

META: 

MISC: 

RESP: 

Pharmacokinetics 

Absorption Rapid/extensive (PO)
Distribution 50% protein binding, extravascular space, then erythrocytes
Metabolism To inactive metabolite
Excretion Kidneys, feces
Half-life 1½-2 hr

Mosby’s Drug Guide for Nursing Students 11th Edition eBook

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